WecLac® Individual Clinical Strains
Clinically Studied
SCI/Patent Supported
SCI/Patent Supported
Bifidobacterium breveBBr60
Study Design
800B CFU/g
Source of Strain
Healthy infant intestines
Deposit Number
PTA-126819(ATCC) No.12915(CGMCC)
Functions
-
Gastrointestinal Health -
Emotional Health -
Metabolic Health -
Maternal & Child Health -
Immune Health -
Oral Health
References
[1]Ye Z, Liang L, Xu Y, Yang J, Li Y. Probiotics Influence Gut Microbiota and Tumor Immune Microenvironment to Enhance Anti-Tumor Efficacy of Doxorubicin. Probiotics Antimicrob Proteins. 2023 Apr 11. doi: 10.1007/s12602-023-10073-7. Epub ahead of print. PMID: 37040014.
[2]Dong Y, Han M, Fei T, Liu H, Gai Z. Utilization of diverse oligosaccharides for growth by Bifidobacterium and Lactobacillus species and their in vitro co-cultivation characteristics. Int Microbiol. 2023 Nov 9. doi: 10.1007/s10123-023-00446-x. Epub ahead of print. PMID: 37946011.
Introduction
Study Design：Randomized, double-blind, placebo-controlled
Subjects：75 overweight or obese adults (BMI ≥ 28 kg/m²) aged between 19 and 45
Dosage：Bifidobacterium breve BBr60 at a dose of 10B CFU per day
Intake Period：12 weeks
Effect of BBr60 on Weight and BMI：After 12 weeks of intervention, The BBr60 group showed an average weight loss of 4.67 kg (p < 0.0001) compared to 2.82 kg in the placebo group (p = 0.0006). Similarly, the BMI in the BBr60 group decreased by 1.49 units (p < 0.0001), while the placebo group exhibited a reduction of 0.93 units (p = 0.057).
Body fat percentage (BFP) was significantly reduced in both groups, with a 2.03% decrease in the BBr60 group (p < 0.0001), compared to a 1.80% reduction in the placebo group (p = 0.150).
Effect on Blood Glucose and Lipid Profiles：The fasting blood glucose (FBG) levels were significantly reduced after 12 weeks with an average decrease from 5.87 mg/dL to 5.26 mg/dL (p < 0.0001)
Effect on Liver and Renal Function：Liver function markers ALT & AST were significantly improved.
Serum Metabolomics Analysis：The BBr60 intervention significantly altered serum metabolites related to key metabolic pathways, particularly amino acid metabolism.
Gut Microbiota Composition：BBr60 supplementation significantly increased beneficial bacteria and improved gut microbiota diversity and richness.
Specialization Advantages
40,000+ Strain Resources
GRAS certified
Allergen free
SCI / Patent supported
High survivability
Non-GMO verified
Clinically studied
High colonisation
Precise function
Industrialization Advantages
High potency
Low water activity
Cost-effectiveness
High stability
Fast delivery
cGMP standard
Excellent batch stability
Stable supply chain
Advanced equipment
Application
-
Dietary Supplement -
Food -
Dairy -
Precision Medicine -
Personal Care -
Feed Additive/Pet
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Lacticaseibacillus paracasei LC86
Bifidobacterium longum subsp. longum BL21
Akkermansia muciniphila Akk11
No. 1033 Longqiao Road, Wujiang Economic and Technological Development Zone, Jiangsu Province, China
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